Pharmaceutical suspension is a liquid dosage form containing finely divided, undissolved drug particles dispersed throughout a liquid vehicle in which the drug exhibits a minimum degree of solubility. Suspension; Stability studies; Extemporaneous preparation. New medicines,vaccines and other medical tools have revolutionised medical practice in the past cen-tury, leading to incredible health improvements. Loss of volatile substances from pharmaceutical dosage forms: Examples: a. Aromatic waters b. In this example, making the suspension more acidic clearly improves stability, although further tests would be required to confirm that stability levels were sufficiently high for a specific application. Many pharmaceutical products are produced in the form of a suspension. The pharmaceutical ingredients solubilize, suspend, thicken, dilute, emulsify, sta-bilize, preserve, color, fl avor, and fashion medici-nal agents into effi cacious and appealing dosage forms. Academia.edu is a platform for academics to share research papers. A number of plant gums have been used as suspending agent in suspenstion formulations. Published by the Pharmaceutical Press 1 Lambeth High Street, London SE1 7JN, UK 1559 St Paul Avenue, Gurnee, IL 60031, USA Pharmaceutical Press 2010 is a trade mark of Pharmaceutical Press Pharmaceutical Press is the publishing division of the Royal Pharmaceutical Society of Great Britain First edition published 2006 Second edition published 2010 Active Pharmaceutical Ingredients make up the dosage forms. Suspensions are usually dispensed in bottles or sachets and are taken from a spoon. Extemporaneous Formulation, MOH 2015 Pharmaceutical Services Division, Ministry of Health Malaysia Lot 36, Jalan Universiti, 46350 Petaling Jaya, Selangor. The main advantages and disadvantages of Pharmaceutical Suspension are stated below: Advantages. c. In suspension: when very fine powder is used a part of suspending agent will dissolve then precipitate as crystal. Indirectly, these medical technology advances Elixirs c. Spirits d. Some types of tablets which contain aromatic water (Nitroglycerin tablets) 3. A pharmaceutical suspension thermodynamically unstable system it should stabilized by adding suitable suspending agent [1, 9]. i) It is easy to dispense unstable or degradable drugs in solution form. The internal phase consisting of insoluble solid particles having a specific range of size which is maintained uniformly through out the suspending vehicle with aid of single or combination of suspending agent. In dependent suspension Conclusion. The Thus, the suspension system includes springs, shock absorbers and their mountings.The suspension system of a motor vehicle is divided into the rear end suspension and front end suspension.. Types of Suspension System. The redispersibility of suspensions D.A. Front End Suspension System; Rigid axle front suspension. Each type of dosage form is unique in its physical and pharmaceutical characteristics. These varied preparations provide the manufac- https://pharmaceuticaltechukm.blogspot.com/2014/05/suspension.html Independent front suspension After dilution, it is important that the drug be homogeneously dispersed before administration. Concentrate for solution for infusion (sterile concentrate). forms that are widely acceptable of poorly soluble drugs with different therapeutic purpose. AEROSOLS Pharmaceutical aerosols are products that are packaged un-der pressure and contain therapeutically active ingredients that The suspension also typically includes an antimicrobial agent (e.g., polymeric quaternary ammonium compound), an antimicrobial system (e.g., borate/polyol complex system) or both. Accurate and effective pharmaceutical formulation is a key skill which must be mastered by all student pharmacists and pharmaceutical technicians. The rheological pro-perties of both liquid and semi-solid pharmaceutical products are impor-tant for the bottling process (pumps, dispensers) and for the selection of suitable packaging. In this stage, the reproducibility on the API’s particle control in the suspension and its stability should be confirmed. There are reports about the successful The selection of the proper excipients (surfactants, viscosity imparting agents etc.) Suspension systems can be broadly classified into two subgroups – Dependent and Independent. ADVERTISEMENTS: ii) Suspension is the only choice if the drug is not soluble in water and non-aqueous solvent is not acceptable, e.g., corticosteroids suspension. This dosage form is used for providing a liquid dosage form for insoluble drugs.. In the formulation of pharmaceutical suspensions, achieving product stability is critical, but can be demanding and time-consuming. 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